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Testing the "toxin hypothesis of allergy": Mast cells, IgE, and innate and acquired immune responses to venoms

Work in mice indicates that innate functions of mast cells, particularly degradation of venom toxins by mast cell-derived proteases, can enhance resistance to certain arthropod or reptile venoms. Recent reports indicate that acquired Th2 immune responses associated with the production of IgE antibod...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Curr Opin Immunol
Main Authors: Tsai, Mindy, Starkl, Philipp, Marichal, Thomas, Galli, Stephen J.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4593748/
https://ncbi.nlm.nih.gov/pubmed/26210895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2015.07.001
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