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Structure and biosynthesis of a macrocyclic peptide containing an unprecedented lysine-to-tryptophan crosslink

Streptococcal bacteria use peptide signals as a means of intraspecies communication. These peptides can contain unusual post-translational modifications providing opportunities for expanding our understanding of Nature's chemical and biosynthetic repertoires. Herein we have combined tools from...

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Udgivet i:Nat Chem
Main Authors: Schramma, Kelsey R., Bushin, Leah B., Seyedsayamdost, Mohammad R.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4443489/
https://ncbi.nlm.nih.gov/pubmed/25901822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchem.2237
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