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Mechanism of pyranopterin ring formation in molybdenum cofactor biosynthesis

The molybdenum cofactor (Moco) is essential for all kingdoms of life, plays central roles in various biological processes, and must be biosynthesized de novo. During Moco biosynthesis, the characteristic pyranopterin ring is constructed by a complex rearrangement of guanosine 5′-triphosphate (GTP) i...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Hover, Bradley M., Tonthat, Nam K., Schumacher, Maria A., Yokoyama, Kenichi
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4443348/
https://ncbi.nlm.nih.gov/pubmed/25941396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1500697112
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