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Identification of a cyclic nucleotide as a cryptic intermediate in molybdenum cofactor biosynthesis

The molybdenum cofactor (Moco) is a redox cofactor found in all kingdoms of life and its biosynthesis is essential for survival of many organisms including humans. The first step of Moco biosynthesis is a unique transformation of GTP into cyclic pyranopterin monophosphate (cPMP). In bacteria, MoaA a...

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Detalhes bibliográficos
Main Authors: Hover, Bradley M., Loksztejn, Anna, Ribeiro, Anthony A., Yokoyama, Kenichi
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3777439/
https://ncbi.nlm.nih.gov/pubmed/23627491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja401781t
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