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Assessment of the effect of ketamine on cytochrome P450 isoforms activity in rats by cocktail method
Cocktail method was used to evaluate the influence of ketamine on the activities of CYP450 isoforms CYP1A2, CYP2D6, CYP3A4, CYP2C19, CYP2C9 and CYP2B6, which were reflected by the changes of pharmacokinetic parameters of six specific probe drugs phenacetin, metroprolol, midazolam, omeprazole, tolbut...
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| Publicado no: | Int J Clin Exp Med |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
e-Century Publishing Corporation
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4443184/ https://ncbi.nlm.nih.gov/pubmed/26064350 |
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