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Regulation of autotaxin expression and secretion by lysophosphatidate and sphingosine 1-phosphate
Autotaxin (ATX) is a secreted enzyme, which produces extracellular lysophosphatidate (LPA) from lysophosphatidylcholine (LPC). LPA activates six G protein-coupled receptors and this is essential for vasculogenesis during embryonic development. ATX is also involved in wound healing and inflammation,...
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| Publicado en: | J Lipid Res |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The American Society for Biochemistry and Molecular Biology
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4442871/ https://ncbi.nlm.nih.gov/pubmed/25896349 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M057661 |
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