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Ruthenium-Catalyzed Cycloaddition of 1-Haloalkynes with Nitrile Oxides and Organic Azides; Synthesis of 4-Halo Isoxazoles and 5-Halo Triazoles

(Cyclopentadienyl)(cyclooctadiene) ruthenium(II) chloride [CpRuCl(cod)] catalyzes the reaction between nitrile oxides and electronically deficient 1-choro-, 1-bromo- and 1-iodoalkynes leading to 4-haloisoxazoles. Organic azides are also suitable 1,3-dipoles, resulting in 5-halo-1,2,3-triazoles. Thes...

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Bibliografiset tiedot
Julkaisussa:Chemistry
Päätekijät: Oakdale, James S., Sit, Rakesh K., Fokin, Valery V.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4442801/
https://ncbi.nlm.nih.gov/pubmed/25059647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201402559
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