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Modulation of Intercellular Junctions by Cyclic-ADT Peptides as a Method to Reversibly Increase Blood-Brain Barrier Permeability

It is challenging to deliver molecules to the brain for diagnosis and treatment of brain diseases. This is primarily due to the presence of the blood-brain barrier (BBB), which restricts the entry of many molecules into the brain. In this study, cyclic ADT peptides (ADTC1, ADTC5, and ADTC6) have bee...

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Detalhes bibliográficos
Publicado no:J Pharm Sci
Main Authors: Laksitorini, Marlyn D., Kiptoo, Paul K., On, Ngoc H., Thliveris, James A., Miller, Donald W., Siahaan, Teruna J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4442687/
https://ncbi.nlm.nih.gov/pubmed/25640479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jps.24309
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