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Enhancement of Drug Absorption through the Blood Brain Barrier and Inhibition of Intercellular Tight Junction Resealing by E-cadherin Peptides

E-cadherin-mediated cell-cell interactions in the zonula adherens play an important role in the formation of the intercellular tight junctions found in the blood-brain barrier. However, it is also responsible for the low permeation of drugs into the brain. In this study, HAV6 peptide derived from th...

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Detalhes bibliográficos
Main Authors: Kiptoo, Paul, Sinaga, Ernawati, Calcagno, Anna M., Zhao, Hong, Kobayashi, Naoki, Tambunan, Usman S.F., Siahaan, Teruna J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078649/
https://ncbi.nlm.nih.gov/pubmed/21128658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp100293m
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