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Crystal structure of human nicotinic acid phosphoribosyltransferase

Nicotinic acid phosphoribosyltransferase (EC 2.4.2.11) (NaPRTase) is the rate-limiting enzyme in the three-step Preiss–Handler pathway for the biosynthesis of NAD. The enzyme catalyzes the conversion of nicotinic acid (Na) and 5-phosphoribosyl-1-pyrophosphate (PRPP) to nicotinic acid mononucleotide...

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Bibliografiske detaljer
Udgivet i:FEBS Open Bio
Main Authors: Marletta, Ada Serena, Massarotti, Alberto, Orsomando, Giuseppe, Magni, Giulio, Rizzi, Menico, Garavaglia, Silvia
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4442680/
https://ncbi.nlm.nih.gov/pubmed/26042198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fob.2015.05.002
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