Gene Therapy Studies in a Canine Model of X-Linked Severe Combined Immunodeficiency

Since the occurrence of T cell leukemias in the original human γ-retroviral gene therapy trials for X-linked severe combined immunodeficiency (XSCID), considerable effort has been devoted to developing safer vectors. This review summarizes gene therapy studies performed in a canine model of XSCID to...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Hum Gene Ther Clin Dev
Hauptverfasser: Felsburg, Peter J., De Ravin, Suk See, Malech, Harry L., Sorrentino, Brian P., Burtner, Christopher, Kiem, Hans-Peter
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mary Ann Liebert, Inc. 2015
Schlagworte:
Invited Reviews
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4442583/
https://ncbi.nlm.nih.gov/pubmed/25603151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/humc.2015.004
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