Role of EXT1 and Glycosaminoglycans in the Early Stage of Filovirus Entry

Filoviruses, including both Ebola virus (EBOV) and Marburg virus (MARV), can infect humans and other animals, causing hemorrhagic fever with a high mortality rate. Entry of these viruses into the host is mediated by a single filoviral glycoprotein (GP). GP is composed of two subunits: GP1, which is...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: O'Hearn, Aileen, Wang, Minxiu, Cheng, Han, Lear-Rooney, Calli M., Koning, Katie, Rumschlag-Booms, Emily, Varhegyi, Elizabeth, Olinger, Gene, Rong, Lijun
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4442511/
https://ncbi.nlm.nih.gov/pubmed/25741008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03689-14
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