Role of EXT1 and Glycosaminoglycans in the Early Stage of Filovirus Entry

Filoviruses, including both Ebola virus (EBOV) and Marburg virus (MARV), can infect humans and other animals, causing hemorrhagic fever with a high mortality rate. Entry of these viruses into the host is mediated by a single filoviral glycoprotein (GP). GP is composed of two subunits: GP1, which is...

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Bibliografske podrobnosti
izdano v:J Virol
Main Authors: O'Hearn, Aileen, Wang, Minxiu, Cheng, Han, Lear-Rooney, Calli M., Koning, Katie, Rumschlag-Booms, Emily, Varhegyi, Elizabeth, Olinger, Gene, Rong, Lijun
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2015
Teme:
Virus-Cell Interactions
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4442511/
https://ncbi.nlm.nih.gov/pubmed/25741008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03689-14
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