Identification of the Essential Role of Viral Bcl-2 for Kaposi's Sarcoma-Associated Herpesvirus Lytic Replication

Kaposi's sarcoma-associated herpesvirus (KSHV) evades host defenses through tight suppression of autophagy by targeting each step of its signal transduction: by viral Bcl-2 (vBcl-2) in vesicle nucleation, by viral FLIP (vFLIP) in vesicle elongation, and by K7 in vesicle maturation. By exploring...

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Liang, Qiming, Chang, Brian, Lee, Patrick, Brulois, Kevin F., Ge, Jianning, Shi, Mude, Rodgers, Mary A., Feng, Pinghui, Oh, Byung-Ha, Liang, Chengyu, Jung, Jae U.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2015
Schlagworte:
Virus-Cell Interactions
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4442505/
https://ncbi.nlm.nih.gov/pubmed/25740994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00102-15
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