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Emergence of Highly Pathogenic Avian Influenza A(H5N1) Virus PB1-F2 Variants and Their Virulence in BALB/c Mice

Influenza A viruses (IAVs) express the PB1-F2 protein from an alternate reading frame within the PB1 gene segment. The roles of PB1-F2 are not well understood but appear to involve modulation of host cell responses. As shown in previous studies, we find that PB1-F2 proteins of mammalian IAVs frequen...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Kamal, Ram P., Kumar, Amrita, Davis, Charles T., Tzeng, Wen-Pin, Nguyen, Tung, Donis, Ruben O., Katz, Jacqueline M., York, Ian A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4442455/
https://ncbi.nlm.nih.gov/pubmed/25787281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03137-14
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