Inhibition of Hepatitis B Virus Gene Expression and Replication by Hepatocyte Nuclear Factor 6

Hepatitis B virus (HBV), a small enveloped DNA virus, chronically infects more than 350 million people worldwide and causes liver diseases from hepatitis to cirrhosis and liver cancer. Here, we report that hepatocyte nuclear factor 6 (HNF6), a liver-enriched transcription factor, can inhibit HBV gen...

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Bibliographic Details
Published in:J Virol
Main Authors: Hao, Ruidong, He, Jing, Liu, Xing, Gao, Guozhen, Liu, Dan, Cui, Lei, Yu, Guojun, Yu, Wenhui, Chen, Yu, Guo, Deyin
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2015
Subjects:
Genome Replication and Regulation of Viral Gene Expression
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4442367/
https://ncbi.nlm.nih.gov/pubmed/25653429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03094-14
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