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X-Ray Structure of the Pestivirus NS3 Helicase and Its Conformation in Solution

Pestiviruses form a genus in the Flaviviridae family of small enveloped viruses with a positive-sense single-stranded RNA genome. Viral replication in this family requires the activity of a superfamily 2 RNA helicase contained in the C-terminal domain of nonstructural protein 3 (NS3). NS3 features t...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Tortorici, M. Alejandra, Duquerroy, Stéphane, Kwok, Jane, Vonrhein, Clemens, Perez, Javier, Lamp, Benjamin, Bricogne, Gerard, Rümenapf, Till, Vachette, Patrice, Rey, Félix A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4442355/
https://ncbi.nlm.nih.gov/pubmed/25653438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03165-14
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