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Effect of Exogenous Penicillin on Penicillin Biosynthesis

The addition of phenoxymethylpenicillin (10 mg/ml) at any time during the penicillin fermentation inhibited further accumulation of the antibiotic in broth but had no effect on growth. Benzylpenicillin, 6-aminopenicillanic acid (6-APA), and some semisynthetic penicillins also showed this effect, but...

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Detalhes bibliográficos
Main Authors: Gordee, Elizabeth Z., Day, L. E.
Formato: Artigo
Idioma:Inglês
Publicado em: 1972
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC444214/
https://ncbi.nlm.nih.gov/pubmed/4208897
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