Succinate dehydrogenase activity regulates PCB3-quinone induced metabolic oxidative stress and toxicity in HaCaT human keratinocytes

Polychlorinated biphenyls (PCBs) and their metabolites are environmental pollutants that are known to have adverse health effects. 1-(4-Chlorophenyl)-benzo-2,5-quinone (4-ClBQ), a quinone-metabolite of 4-Monochlorobiphenyl (PCB3, present in the environment and human blood) is toxic to human skin ker...

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Detalhes bibliográficos
Publicado no:Arch Toxicol
Main Authors: Xiao, Wusheng, Sarsour, Ehab H., Wagner, Brett A., Doskey, Claire M., Buettner, Garry R., Domann, Frederick E., Goswami, Prabhat C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4441874/
https://ncbi.nlm.nih.gov/pubmed/25417049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-014-1407-3
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