Ligand-independent activation of Aryl hydrocarbon receptor signaling in PCB3-quinone treated HaCaT human keratinocytes

Aryl hydrocarbon receptor (AhR) is a ligand-dependent transcription factor that plays a critical role in metabolism, cell proliferation, development, carcinogenesis, and xenobiotic response. In general, dioxin-like polychlorinated biphenyls (PCBs) exhibit a ligand-dependent activation of AhR-signali...

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Detalles Bibliográficos
Publicado en:Toxicol Lett
Main Authors: Xiao, Wusheng, Son, Jyungmean, Vorrink, Sabine U., Domann, Frederick E., Goswami, Prabhat C.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4341842/
https://ncbi.nlm.nih.gov/pubmed/25668756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxlet.2015.02.005
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