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RECQ1 interacts with FEN-1 and promotes binding of FEN-1 to telomeric chromatin

RecQ helicases are a family of highly conserved proteins that maintain genomic stability through their important roles in replication restart mechanisms. Cellular phenotypes of RECQ1 deficiency are indicative of aberrant repair of stalled replication forks, but the molecular functions of RECQ1, the...

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Détails bibliographiques
Publié dans:Biochem J
Auteurs principaux: Sami, Furqan, Lu, Xing, Parvathaneni, Swetha, Roy, Rabindra, Gary, Ronald K., Sharma, Sudha
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4441847/
https://ncbi.nlm.nih.gov/pubmed/25774876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20141021
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