Loading...
Interpretation of pH-activity Profiles for Acid-Base Catalysis from Molecular Simulations
The measurement of reaction rate as a function of pH provides essential information about mechanism. These rates are sensitive to the pK(a) values of amino acids directly involved in catalysis that are often shifted by the enzyme active site environment. Experimentally observed pH-rate profiles are...
Saved in:
| Published in: | Biochemistry |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2015
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4441796/ https://ncbi.nlm.nih.gov/pubmed/25615525 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi5012833 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|