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Stereochemical Assignment of the Protein–Protein Interaction Inhibitor JBIR-22 by Total Synthesis**

Recent reports have highlighted the biological activity associated with a subfamily of the tetramic acid class of natural products. Despite the fact that members of this subfamily act as protein–protein interaction inhibitors that are of relevance to proteasome assembly, no synthetic work has been r...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Healy, Alan R, Izumikawa, Miho, Slawin, Alexandra M Z, Shin-ya, Kazuo, Westwood, Nicholas J
Formato: Artigo
Idioma:Inglês
Publicado em: WILEY-VCH Verlag 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4441253/
https://ncbi.nlm.nih.gov/pubmed/25650886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201411141
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