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TGF-β converts Th1 cells into Th17 cells through stimulation of Runx1 expression

Differentiated CD4(+) T cells preserve plasticity under various conditions. However, the stability of Th1 cells is unclear, as is whether Th1 cells can convert into Th17 cells and thereby contribute to the generation of IFN-γ(+)IL-17(+)CD4(+) T cells, the number of which correlates with severity of...

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Detalhes bibliográficos
Publicado no:Eur J Immunol
Main Authors: Liu, Hou-Pu, T. Cao, Anthony, Feng, Ting, Li, Qingjie, Zhang, Wenbo, Yao, Suxia, Dann, Sara M., Elson, Charles O., Cong, Yingzi
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4441226/
https://ncbi.nlm.nih.gov/pubmed/25605286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201444726
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