Increased production of BDNF in colonic epithelial cells induced by fecal supernatants from diarrheic IBS patients

Colonic brain-derived neurotrophic factor (BDNF) plays an essential role in pathogenesis of abdominal pain in diarrhea-predominant irritable bowel syndrome (IBS-D), but regulation on its expression remains unclear. We investigated the role of fecal supernatants (FSN) from IBS-D patients on regulatin...

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Publicat a:Sci Rep
Autors principals: Wang, Peng, Chen, Fei-Xue, Du, Chao, Li, Chang-Qing, Yu, Yan-Bo, Zuo, Xiu-Li, Li, Yan-Qing
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4441152/
https://ncbi.nlm.nih.gov/pubmed/25998025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep10121
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