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IDH Mutation Analysis in Ewing Sarcoma Family Tumors
BACKGROUND: Isocitrate dehydrogenase (IDH) catalyzes the oxidative decarboxylation of isocitrate to yield α-ketoglutarate (α-KG) with production of reduced nicotinamide adenine dinucleotide (NADH). Dysfunctional IDH leads to reduced production of α-KG and NADH and increased production of 2-hydroxygl...
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Publicado no: | J Pathol Transl Med |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The Korean Society of Pathologists and the Korean Society for Cytopathology
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4440938/ https://ncbi.nlm.nih.gov/pubmed/26018518 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4132/jptm.2015.04.14 |
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