IDH Mutation Analysis in Ewing Sarcoma Family Tumors

BACKGROUND: Isocitrate dehydrogenase (IDH) catalyzes the oxidative decarboxylation of isocitrate to yield α-ketoglutarate (α-KG) with production of reduced nicotinamide adenine dinucleotide (NADH). Dysfunctional IDH leads to reduced production of α-KG and NADH and increased production of 2-hydroxygl...

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Foilsithe in:J Pathol Transl Med
Main Authors: Na, Ki Yong, Noh, Byeong-Joo, Sung, Ji-Youn, Kim, Youn Wha, Santini Araujo, Eduardo, Park, Yong-Koo
Formáid: Artigo
Teanga:Inglês
Foilsithe: The Korean Society of Pathologists and the Korean Society for Cytopathology 2015
Ábhair:
Original Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4440938/
https://ncbi.nlm.nih.gov/pubmed/26018518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4132/jptm.2015.04.14
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