MOZ regulates B-cell progenitors and, consequently, Moz haploinsufficiency dramatically retards MYC-induced lymphoma development

The histone acetyltransferase MOZ (MYST3, KAT6A) is the target of recurrent chromosomal translocations fusing the MOZ gene to CBP, p300, NCOA3, or TIF2 in particularly aggressive cases of acute myeloid leukemia. In this study, we report the role of wild-type MOZ in regulating B-cell progenitor proli...

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Bibliografski detalji
Izdano u:Blood
Glavni autori: Sheikh, Bilal N., Lee, Stanley C. W., El-Saafin, Farrah, Vanyai, Hannah K., Hu, Yifang, Pang, Swee Heng Milon, Grabow, Stephanie, Strasser, Andreas, Nutt, Stephen L., Alexander, Warren S., Smyth, Gordon K., Voss, Anne K., Thomas, Tim
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2015
Teme:
Lymphoid Neoplasia
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4440887/
https://ncbi.nlm.nih.gov/pubmed/25605372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-08-594655
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