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MOZ and BMI1 play opposing roles during Hox gene activation in ES cells and in body segment identity specification in vivo

Hox genes underlie the specification of body segment identity in the anterior–posterior axis. They are activated during gastrulation and undergo a dynamic shift from a transcriptionally repressed to an active chromatin state in a sequence that reflects their chromosomal location. Nevertheless, the p...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Sheikh, Bilal N., Downer, Natalie L., Phipson, Belinda, Vanyai, Hannah K., Kueh, Andrew J., McCarthy, Davis J., Smyth, Gordon K., Thomas, Tim, Voss, Anne K.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4418851/
https://ncbi.nlm.nih.gov/pubmed/25922517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1422872112
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