MOZ and BMI1 play opposing roles during Hox gene activation in ES cells and in body segment identity specification in vivo

Hox genes underlie the specification of body segment identity in the anterior–posterior axis. They are activated during gastrulation and undergo a dynamic shift from a transcriptionally repressed to an active chromatin state in a sequence that reflects their chromosomal location. Nevertheless, the p...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Sheikh, Bilal N., Downer, Natalie L., Phipson, Belinda, Vanyai, Hannah K., Kueh, Andrew J., McCarthy, Davis J., Smyth, Gordon K., Thomas, Tim, Voss, Anne K.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2015
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4418851/
https://ncbi.nlm.nih.gov/pubmed/25922517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1422872112
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