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MOZ and BMI1 play opposing roles during Hox gene activation in ES cells and in body segment identity specification in vivo

Hox genes underlie the specification of body segment identity in the anterior–posterior axis. They are activated during gastrulation and undergo a dynamic shift from a transcriptionally repressed to an active chromatin state in a sequence that reflects their chromosomal location. Nevertheless, the p...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Sheikh, Bilal N., Downer, Natalie L., Phipson, Belinda, Vanyai, Hannah K., Kueh, Andrew J., McCarthy, Davis J., Smyth, Gordon K., Thomas, Tim, Voss, Anne K.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4418851/
https://ncbi.nlm.nih.gov/pubmed/25922517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1422872112
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