MOZ and BMI1 play opposing roles during Hox gene activation in ES cells and in body segment identity specification in vivo

Hox genes underlie the specification of body segment identity in the anterior–posterior axis. They are activated during gastrulation and undergo a dynamic shift from a transcriptionally repressed to an active chromatin state in a sequence that reflects their chromosomal location. Nevertheless, the p...

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書目詳細資料
發表在:Proc Natl Acad Sci U S A
Main Authors: Sheikh, Bilal N., Downer, Natalie L., Phipson, Belinda, Vanyai, Hannah K., Kueh, Andrew J., McCarthy, Davis J., Smyth, Gordon K., Thomas, Tim, Voss, Anne K.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2015
主題:
Biological Sciences
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4418851/
https://ncbi.nlm.nih.gov/pubmed/25922517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1422872112
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