MOZ regulates B-cell progenitors and, consequently, Moz haploinsufficiency dramatically retards MYC-induced lymphoma development

The histone acetyltransferase MOZ (MYST3, KAT6A) is the target of recurrent chromosomal translocations fusing the MOZ gene to CBP, p300, NCOA3, or TIF2 in particularly aggressive cases of acute myeloid leukemia. In this study, we report the role of wild-type MOZ in regulating B-cell progenitor proli...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Blood
Hlavní autoři: Sheikh, Bilal N., Lee, Stanley C. W., El-Saafin, Farrah, Vanyai, Hannah K., Hu, Yifang, Pang, Swee Heng Milon, Grabow, Stephanie, Strasser, Andreas, Nutt, Stephen L., Alexander, Warren S., Smyth, Gordon K., Voss, Anne K., Thomas, Tim
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2015
Témata:
Lymphoid Neoplasia
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4440887/
https://ncbi.nlm.nih.gov/pubmed/25605372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-08-594655
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky