טוען...
Secondary mutations as mediators of resistance to targeted therapy in leukemia
The advent of small molecule-based targeted therapy has improved the treatment of both acute and chronic leukemias. Resistance to small molecule inhibitors has emerged as a common theme. The most frequent mode of acquired resistance is the acquisition of point mutations in the kinase domain. FLT3 in...
שמור ב:
| הוצא לאור ב: | Blood |
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| Main Authors: | , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Society of Hematology
2015
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4440880/ https://ncbi.nlm.nih.gov/pubmed/25795921 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-10-605808 |
| תגים: |
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