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Nanoparticulate Delivery of Agents for Induced Elastogenesis in 3-Dimensional Collagenous Matrices

The degradation of elastic matrix in the infrarenal aortic wall is a critical parameter underlying the formation and progression of abdominal aortic aneurysms (AAAs). It is mediated by the chronic overexpression of matrix metalloproteases (MMPs) -2 and -9, leading to a progressive loss of elasticity...

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Detalhes bibliográficos
Publicado no:J Tissue Eng Regen Med
Main Authors: Venkataraman, Lavanya, Sivaraman, Balakrishnan, Vaidya, Pratik, Ramamurthi, Anand
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4440849/
https://ncbi.nlm.nih.gov/pubmed/24737693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/term.1889
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