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Rapid parallel synthesis of bioactive folded cyclotides using a tea-bag approach
We report here for the first time the rapid parallel production of bioactive folded cyclotides by using Fmoc-based solid-phase peptide synthesis in combination with a tea-bag approach. Using this approach we efficiently synthesized 15 different analogs of the CXCR4 antagonist cyclotide MCo-CVX-5c. C...
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| Izdano u: | Chembiochem |
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| Glavni autori: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2015
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4440831/ https://ncbi.nlm.nih.gov/pubmed/25663016 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201402691 |
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