The Neisseria meningitidis ADP-Ribosyltransferase NarE Enters Human Epithelial Cells and Disrupts Epithelial Monolayer Integrity

Many pathogenic bacteria utilize ADP-ribosylating toxins to modify and impair essential functions of eukaryotic cells. It has been previously reported that Neisseria meningitidis possesses an ADP-ribosyltransferase enzyme, NarE, retaining the capacity to hydrolyse NAD and to transfer ADP-ribose moie...

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Veröffentlicht in:PLoS One
Hauptverfasser: Valeri, Maria, Zurli, Vanessa, Ayala, Inmaculada, Colanzi, Antonino, Lapazio, Lucia, Corda, Daniela, Soriani, Marco, Pizza, Mariagrazia, Rossi Paccani, Silvia
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4440719/
https://ncbi.nlm.nih.gov/pubmed/25996923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0127614
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