Identification of the Adapter Molecule MTSS1 as a Potential Oncogene-Specific Tumor Suppressor in Acute Myeloid Leukemia

The adapter protein metastasis suppressor 1 (MTSS1) is implicated as a tumor suppressor or tumor promoter, depending on the type of solid cancer. Here, we identified Mtss1 expression to be increased in AML subsets with favorable outcome, while suppressed in high risk AML patients. High expression of...

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Publié dans:PLoS One
Auteurs principaux: Schemionek, Mirle, Kharabi Masouleh, Behzad, Klaile, Yvonne, Krug, Utz, Hebestreit, Katja, Schubert, Claudia, Dugas, Martin, Büchner, Thomas, Wörmann, Bernhard, Hiddemann, Wolfgang, Berdel, Wolfgang E., Brümmendorf, Tim H., Müller-Tidow, Carsten, Koschmieder, Steffen
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4440712/
https://ncbi.nlm.nih.gov/pubmed/25996952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0125783
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