Identification of the Adapter Molecule MTSS1 as a Potential Oncogene-Specific Tumor Suppressor in Acute Myeloid Leukemia

The adapter protein metastasis suppressor 1 (MTSS1) is implicated as a tumor suppressor or tumor promoter, depending on the type of solid cancer. Here, we identified Mtss1 expression to be increased in AML subsets with favorable outcome, while suppressed in high risk AML patients. High expression of...

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Vydáno v:PLoS One
Hlavní autoři: Schemionek, Mirle, Kharabi Masouleh, Behzad, Klaile, Yvonne, Krug, Utz, Hebestreit, Katja, Schubert, Claudia, Dugas, Martin, Büchner, Thomas, Wörmann, Bernhard, Hiddemann, Wolfgang, Berdel, Wolfgang E., Brümmendorf, Tim H., Müller-Tidow, Carsten, Koschmieder, Steffen
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4440712/
https://ncbi.nlm.nih.gov/pubmed/25996952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0125783
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