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Isoprenoids and Related Pharmacological Interventions: Potential Application in Alzheimer’s Disease
Two major isoprenoids, farnesyl pyrophosphate and geranylgeranyl pyrophosphate, serve as lipid donors for the posttranslational modification (known as prenylation) of proteins that possess a characteristic C-terminal motif. The prenylation reaction is catalyzed by prenyltransferases. The lipid preny...
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| Veröffentlicht in: | Mol Neurobiol |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4440689/ https://ncbi.nlm.nih.gov/pubmed/22418893 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-012-8253-1 |
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