The kinase activity of the Ser/Thr kinase BUB1 promotes TGF-β signaling

Transforming growth factor-β (TGFβ) signaling regulates cell proliferation, differentiation, and development. The binding of TGFβ to TGFβ receptor 2 (TGFBRII) induces the interaction between TGFβ receptor 1 (TGFBRI) and TGFBRII, leading to the phosphorylation and activation of transcriptional regula...

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Vydáno v:Sci Signal
Hlavní autoři: Nyati, Shyam, Schinske-Sebolt, Katrina, Pitchiaya, Sethuramasundaram, Chekhovskiy, Katerina, Chator, Areeb, Chaudhry, Nauman, Dosch, Joseph, Van Dort, Marcian E., Varambally, Sooryanarayana, Kumar-Sinha, Chandan, Nyati, Mukesh Kumar, Ray, Dipankar, Walter, Nils G., Yu, Hongtao, Ross, Brian Dale, Rehemtulla, Alnawaz
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4440544/
https://ncbi.nlm.nih.gov/pubmed/25564677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2005379
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