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Targeted therapy of chronic myeloid leukemia

Inhibition of BCR-ABL with kinase inhibitors has become a well-accepted strategy for targeted therapy of Philadelphia-positive (Ph(+)) chronic myeloid leukemia (CML), and has been shown to be highly effective in controlling the disease. However, BCR-ABL kinase inhibitors do not efficiently kill leuk...

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Détails bibliographiques
Publié dans:Biochem Pharmacol
Auteurs principaux: Sullivan, Con, Peng, Cong, Chen, Yaoyu, Li, Dongguang, Li, Shaoguang
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4440481/
https://ncbi.nlm.nih.gov/pubmed/20470758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2010.05.001
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