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Genetic linkage analysis in the age of whole-genome sequencing

For many years, linkage analysis was the primary tool used for the genetic mapping of Mendelian and complex traits with familial aggregation. Linkage analysis was largely supplanted by the wide adoption of genome-wide association studies (GWASs). However, with the recent increased use of whole-genom...

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書目詳細資料
發表在:Nat Rev Genet
Main Authors: Ott, Jurg, Wang, Jing, Leal, Suzanne M.
格式: Artigo
語言:Inglês
出版: 2015
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4440411/
https://ncbi.nlm.nih.gov/pubmed/25824869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrg3908
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