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Genetic linkage analysis in the age of whole-genome sequencing

For many years, linkage analysis was the primary tool used for the genetic mapping of Mendelian and complex traits with familial aggregation. Linkage analysis was largely supplanted by the wide adoption of genome-wide association studies (GWASs). However, with the recent increased use of whole-genom...

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Detalhes bibliográficos
Publicado no:Nat Rev Genet
Main Authors: Ott, Jurg, Wang, Jing, Leal, Suzanne M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4440411/
https://ncbi.nlm.nih.gov/pubmed/25824869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrg3908
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