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Assessing dose–response relationships for endocrine disrupting chemicals (EDCs): a focus on non-monotonicity

The fundamental principle in regulatory toxicology is that all chemicals are toxic and that the severity of effect is proportional to the exposure level. An ancillary assumption is that there are no effects at exposures below the lowest observed adverse effect level (LOAEL), either because no effect...

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Detalhes bibliográficos
Publicado no:Environ Health
Main Authors: Zoeller, R Thomas, Vandenberg, Laura N
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4440251/
https://ncbi.nlm.nih.gov/pubmed/25971795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12940-015-0029-4
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