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DNA demethylation and invasive cancer: implications for therapeutics
One of the hallmarks of cancer is aberrant DNA methylation, which is associated with abnormal gene expression. Both hypermethylation and silencing of tumour suppressor genes as well as hypomethylation and activation of prometastatic genes are characteristic of cancer cells. As DNA methylation is rev...
Tallennettuna:
| Julkaisussa: | Br J Pharmacol |
|---|---|
| Päätekijät: | , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
BlackWell Publishing Ltd
2015
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4439869/ https://ncbi.nlm.nih.gov/pubmed/25134627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12885 |
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