Early but limited effects of raltegravir intensification on CD4 T cell reconstitution in HIV-infected patients with an immunodiscordant response to antiretroviral therapy

BACKGROUND: Immune hyperactivation in immunodiscordant patients can induce residual HIV replication and limit CD4 T cell recovery. We assessed the impact of raltegravir intensification on CD4 T cell recovery and viral persistence. METHODS: We performed a randomized, controlled, pilot trial. Patients...

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書目詳細資料
發表在:J Antimicrob Chemother
Main Authors: Negredo, Eugènia, Massanella, Marta, Puertas, Maria C., Buzón, Maria J., Puig, Jordi, Pérez-Alvárez, Núria, Pérez-Santiago, Josué, Bonjoch, Anna, Moltó, José, Jou, Antoni, Echeverría, Patricia, Llibre, Josep M., Martínez-Picado, Javier, Clotet, Bonaventura, Blanco, Julià
格式: Artigo
語言:Inglês
出版: Oxford University Press 2013
主題:
Original Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4439517/
https://ncbi.nlm.nih.gov/pubmed/23677919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkt183
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