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Modelling HIV-1 2-LTR dynamics following raltegravir intensification

A model of reservoir activation and viral replication is introduced accounting for the production of 2-LTR HIV-1 DNA circles following antiviral intensification with the HIV integrase inhibitor raltegravir, considering contributions of de novo infection events and exogenous sources of infected cells...

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Bibliografiske detaljer
Main Authors: Luo, Rutao, Cardozo, E. Fabian, Piovoso, Michael J., Wu, Hulin, Buzon, Maria J., Martinez-Picado, Javier, Zurakowski, Ryan
Format: Artigo
Sprog:Inglês
Udgivet: The Royal Society 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3673152/
https://ncbi.nlm.nih.gov/pubmed/23658114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2013.0186
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