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Spectrum of UGT1A1 Variations in Chinese Patients with Crigler-Najjar Syndrome Type II

Crigler–Najjar Syndrome type II (CNS-II) is an autosomal recessive hereditary condition of unconjugated hyperbilirubinemia without hemolysis, with bilirubin levels ranging from 102.6 μmol/L to 342 μmol/L. CNS-II is caused by a deficiency of UDP-glucuronyl transferase (UGT), which is encoded by the U...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Li, Lufeng, Deng, Guohong, Tang, Yi, Mao, Qing
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4439166/
https://ncbi.nlm.nih.gov/pubmed/25993113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0126263
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