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Maximizing gene delivery efficiencies of cationic helical polypeptides via balanced membrane penetration and cellular targeting

The application of non-viral gene delivery vectors is often accompanied with the poor correlation between transfection efficiency and the safety profiles of vectors: vectors with high transfection efficiencies often suffer from high toxicities, making it unlikely to improve their efficiencies by inc...

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Détails bibliographiques
Publié dans:Biomaterials
Auteurs principaux: Zheng, Nan, Yin, Lichen, Song, Ziyuan, Ma, Liang, Tang, Haoyu, Gabrielson, Nathan P., Lu, Hua, Cheng, Jianjun
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4439006/
https://ncbi.nlm.nih.gov/pubmed/24211080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2013.09.090
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