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A Reactive and Bioactive Cationic α-Helical Polypeptide Template for Non-Viral Gene Delivery

[Image: see text] Poly(γ-(4-vinylbenzyl)-l-glutamate) (PVBLG) served as a bioactive and reactive template for the generation of a library of cationic α-helical polypeptides for gene delivery. The top performing polymer outperformed 25-kDa polyethylenimine by 12-fold. Preliminary data indicates that...

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Detalhes bibliográficos
Main Authors: Gabrielson, Nathan P., Lu, Hua, Yin, Lichen, Li, Dong, Wang, Fei, Cheng, Jianjun
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3555134/
https://ncbi.nlm.nih.gov/pubmed/22162307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201104262
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