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Mitochondrial function and regulation of macrophage sterol metabolism and inflammatory responses

The aim of this review is to explore the role of mitochondria in regulating macrophage sterol homeostasis and inflammatory responses within the aetiology of atherosclerosis. Macrophage generation of oxysterol activators of liver X receptors (LXRs), via sterol 27-hydroxylase, is regulated by the rate...

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Detalhes bibliográficos
Publicado no:World J Cardiol
Main Authors: Graham, Annette, Allen, Anne-Marie
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Inc 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4438467/
https://ncbi.nlm.nih.gov/pubmed/26015858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4330/wjc.v7.i5.277
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