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Continuous de novo biosynthesis of haem and its rapid turnover to bilirubin are necessary for cytoprotection against cell damage

It is well known that haem serves as the prosthetic group of various haemoproteins that function in oxygen transport, respiratory chain, and drug metabolism. However, much less is known about the functions of the catabolites of haem in mammalian cells. Haem is enzymatically degraded to iron, carbon...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Takeda, Taka-aki, Mu, Anfeng, Tai, Tran Tien, Kitajima, Sakihito, Taketani, Shigeru
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4438432/
https://ncbi.nlm.nih.gov/pubmed/25990790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep10488
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