Novel Role for Cyclophilin A in Regulation of Chondrogenic Commitment and Endochondral Ossification

Recent studies showed that cyclophilin A (CypA) promotes NF-κB/p65 nuclear translocation, resulting in enhanced NF-κB activity and altered expression of its target genes, such as the Sox9 transcriptional factor, which plays a critical role in chondrogenic differentiation and endochondral ossificatio...

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Vydáno v:Mol Cell Biol
Hlavní autoři: Guo, Mian, Shen, Jia, Kwak, Jin Hee, Choi, Bogyu, Lee, Min, Hu, Shen, Zhang, Xinli, Ting, Kang, Soo, Chia B., Chiu, Robert H.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4438250/
https://ncbi.nlm.nih.gov/pubmed/25870110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01414-14
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